Neurobrucellosis: Challenges for Therapy

Neurobrucellosis.

Brucellosis remains an important health problem in some parts of the world. The disease has virtually disappeared in Western countries but is still endemic in others. In Kuwait, with a population of 1.6 million, a total number of 1168 fresh cases of brucellosis were reported in 1985, an incidence of 68.9/100,000 population. The general presentation of brucellosis remains well recognized and is ...

neurobrucellosis and steroid therapy

Neurobrucellosis.

Brucellosis, which is endemic in Saudi Arabia, can present as a disease with multisystem involvement. Occasionally the organisms invade the central nervous system producing varied neurological manifestations. Often the clinical diagnosis of neurobrucellosis is not straight forward and is obscure. Certain criteria have to be fulfilled for the definitive diagnosis of neurobrucellosis. We report 2...

Cochlear Implantation in Neurobrucellosis.

BACKGROUND Neurobrucellosis is a disease consisting of a wide spectrum of complications such as peripheral neuropathy, cranial nerve involvement, ataxia, meningeal irritation, paraplegia, seizures, coma, and even death. The vestibulocochlear nerve seems to be the most commonly affected cranial nerve (10%). We present a patient with neurobrucellosis whose auditory perception and speech intelligi...

Serological diagnosis of neurobrucellosis.

The presence of antibodies was determined in the serum and cerebrospinal fluid in six patients with neurobrucellosis using the Rose Bengal test, the microdilution agglutination test, and the Coombs' test. Four of the patients were followed up for more than three months. The Rose Bengal test and the microagglutination test were positive in cerebrospinal fluid in five of the six cases at some sta...